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DNA Damage Atlas |
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DNA Damage Atlas |
Basic Information
Dataset ID:
GSE202567
PMID:
35764636
Technique Type:
CSR-HTGTS
Publication:
SHLD1 is dispensable for 53BP1-dependent V(D)J recombination but critical for productive class switch recombination
First Author:
Estelle Vincendeau
Last Author:
Ludovic Deriano
Year:
2022
Journal:
Nature Communications
Access Link:
Samples ( 18 )
| Sample Name | Cell Line/Tissue | Organism | Treatment | Genotype | In-situ Treatment | Cell Phase | Bait/Targeted Break | Technique | fastqc |
| GSM6124561-XF_970_AltN171 | Spleen B cell | Mus musculus | cytokine stimulation;ABLki | WT | / | / | target locus: non-coding IgH Sm-Sa deletion | CSR-HTGTS | |
| GSM6124562-XF_971_AltN171 | Spleen B cell | Mus musculus | cytokine stimulation;ABLki | WT | / | / | target locus: non-coding IgH Sm-Sa deletion | CSR-HTGTS | |
| GSM6124563-XF_972_AltN171 | Spleen B cell | Mus musculus | cytokine stimulation;ABLki | WT | / | / | target locus: non-coding IgH Sm-Sa deletion | CSR-HTGTS | |
| GSM6124564-XF_973_AltN171 | Spleen B cell | Mus musculus | cytokine stimulation;ABLki | Shld1-/- | / | / | target locus: Ia deletion in non-coding IgH Sm-Sa deletion cells | CSR-HTGTS | |
| GSM6124565-XF_974_AltN171 | Spleen B cell | Mus musculus | cytokine stimulation;ABLki | Shld1-/- | / | / | target locus: Ia deletion in non-coding IgH Sm-Sa deletion cells | CSR-HTGTS | |
| GSM6124566-XF_975_AltN171 | Spleen B cell | Mus musculus | cytokine stimulation;ABLki | Shld1-/- | / | / | target locus: Ia deletion in non-coding IgH Sm-Sa deletion cells | CSR-HTGTS | |
| GSM6124567-XF_976_AltN171 | splenic B cells | Mus musculus | cytokine stimulation;ABLki | XLF-/- | / | / | target locus: Ia deletion in non-coding IgH Sm-Sa deletion cells | CSR-HTGTS | |
| GSM6124568-XF_977_AltN171 | Spleen B cell | Mus musculus | cytokine stimulation;ABLki | XLF-/- | / | / | target locus: Ia deletion in non-coding IgH Sm-Sa deletion cells | CSR-HTGTS | |
| GSM6124569-XF_978_AltN171 | Spleen B cell | Mus musculus | cytokine stimulation;ABLki | XLF-/- | / | / | target locus: Ia deletion in non-coding IgH Sm-Sa deletion cells | CSR-HTGTS | |
| GSM6124570-XF_979_AltN171 | Spleen B cell | Mus musculus | cytokine stimulation;ABLki | Shld1-/-XLF-/- | / | / | target locus: three CBEs insertion downstream of Cg2a in Ia deleted cells | CSR-HTGTS | |
| GSM6124571-XF_980_AltN171 | Spleen B cell | Mus musculus | cytokine stimulation;ABLki | Shld1-/-XLF-/- | / | / | target locus: three CBEs insertion downstream of Cg2a in Ia deleted cells | CSR-HTGTS | |
| GSM6124572-XF_981_AltN171 | Spleen B cell | Mus musculus | cytokine stimulation;ABLki | Shld1-/-XLF-/- | / | / | target locus: three CBEs insertion downstream of Cg2a in Ia deleted cells | CSR-HTGTS | |
| GSM6124573-XF_982_AltN172 | Spleen B cell | Mus musculus | cytokine stimulation;ABLki | WT | / | / | target locus: non-coding IgH Sm-Sa deletion | CSR-HTGTS | |
| GSM6124574-XF_983_AltN172 | Spleen B cell | Mus musculus | cytokine stimulation;ABLki | WT | / | / | target locus: non-coding IgH Sm-Sa deletion | CSR-HTGTS | |
| GSM6124575-XF_984_AltN172 | Spleen B cell | Mus musculus | cytokine stimulation;ABLki | WT | / | / | target locus: non-coding IgH Sm-Sa deletion | CSR-HTGTS | |
| GSM6124576-XF_985_AltN172 | Spleen B cell | Mus musculus | cytokine stimulation;ABLki | 53BP1-/- | / | / | target locus: Single CBE insertion with the same orientation as 3'CBEs in non-coding IgH Sm-Sa deletion cells | CSR-HTGTS | |
| GSM6124577-XF_986_AltN172 | Spleen B cell | Mus musculus | cytokine stimulation;ABLki | 53BP1-/- | / | / | target locus: Single CBE insertion with the same orientation as 3'CBEs in non-coding IgH Sm-Sa deletion cells | CSR-HTGTS | |
| GSM6124578-XF_987_AltN172 | Spleen B cell | Mus musculus | cytokine stimulation;ABLki | 53BP1-/- | / | / | target locus: Single CBE insertion with the same orientation as 3'CBEs in non-coding IgH Sm-Sa deletion cells | CSR-HTGTS |
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